Is my sore throat from COVID-19 or from strep throat? What’s the difference? For starters, COVID-19 is a viral infection and like the flu, colds or other viral infections, these often are accompanied by respiratory symptoms. Strep throat is not like your common cold, flu or COVID-19. It’s actually caused by a bacterial infection to the throat and tonsils. We get that it’s confusing, but don’t always assume it’s COVID-19 ...