" What’s the difference between sprains and strains? Sprain: an injury to the ligaments, which connect the end of one bone to another Strain: an injury to a muscle of tendon (which attaches muscle to bone) When it comes to treating minor injuries, it’s importance to practice the RICE method: rest, ice, compression, and elevation. If the pain is persistent, you may want to seek medical attention and be advised on the best treatment ...